SEMA7A antibody (AA 169-390)

Catalog No. ABIN7193548

Product Details anti-SEMA7A Antibody

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Binding Specificity: AA 169-390

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SEMA7A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: CD108 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli.

Clone: 1D5G8

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SEMA7A

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Alternative Name: CD108 (SEMA7A Products)

Background:

Description:

This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Aliases: SEMA7A, JMH, SEMAL, CDw108, SEMAK1, H-Sema-L, H-SEMA-K1

Molecular Weight: 74.8kDa

Gene ID: 8482

UniProt: O75326

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size