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SEMA7A Products

(Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
The protein encoded by this gene binds to cell surfaces through a glycosylphosphatidylinositol (GPI) linkage. The encoded glycoprotein is found on activated lymphocytes and erythrocytes. This protein may be involved in immunomodulatory and neuronal processes. Defects in this gene can result in loss of bone mineral density (BMD). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

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Featured SEMA7A Categories

SEMA7A Antibodies

High quality antibodies with extensive validation data.

SEMA7A ELISA Kits

Reliable ELISA kits for a wide range of species.

SEMA7A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SEMA7A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN7193548
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IP, FACS
Validations
  • (2)
  • (2)
Cat. No. ABIN93945
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN521934
Quantity 100 μg
Datasheet Datasheet

Recommended SEMA7A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959360
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970097
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959359
Quantity 96 tests
Datasheet Datasheet

Recommended SEMA7A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275570
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275564
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1319500
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SEMA7A products

Franco, Reihani, Dupuis, Collec, Billette de Villemeur, de Person, Moussa, Berger, Belmatoug, Le Van Kim: "Semaphorin 7A: A novel marker of disease activity in Gaucher disease." in: American journal of hematology, Vol. 95, Issue 5, pp. 483-491, (2020) (PubMed).

Manini, Ruaro, Sgarra, Bartolini, Caponnetto, Ius, Skrap, Di Loreto, Beltrami, Manfioletti, Cesselli: "Semaphorin-7A on Exosomes: A Promigratory Signal in the Glioma Microenvironment." in: Cancers, Vol. 11, Issue 6, (2019) (PubMed).

Chen, Wang, Jia, Wang, Ren: "Anti-Semaphorin-7A single chain antibody demonstrates beneficial effects on pulmonary inflammation during acute lung injury." in: Experimental and therapeutic medicine, Vol. 15, Issue 3, pp. 2356-2364, (2018) (PubMed).

Esnault, Torr, Bernau, Johansson, Kelly, Sandbo, Jarjour: "Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170207, (2017) (PubMed).

Roth, Köhler, Schneider, Granja, Rosenberger: "Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146930, (2016) (PubMed).

Peng, Moore, Mathur, Zhou, Sun, Gan, Herazo-Maya, Kaminski, Hu, Pan, Ryu, Osafo-Addo, Homer, Feghali-Bostwick, Fares, Gulati, Hu, Lee, Elias, Herzog: "Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 12, pp. 4056-4070, (2016) (PubMed).

Esnault, Kelly, Shen, Johansson, Malter, Jarjour: "IL-3 Maintains Activation of the p90S6K/RPS6 Pathway and Increases Translation in Human Eosinophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2529-39, (2015) (PubMed).

Morote-Garcia, Napiwotzky, Köhler, Rosenberger: "Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 35, pp. 14146-51, (2012) (PubMed).

Gan, Reilkoff, Peng, Russell, Chen, Mathai, Homer, Gulati, Siner, Elias, Bucala, Herzog: "Role of semaphorin 7a signaling in transforming growth factor ?1-induced lung fibrosis and scleroderma-related interstitial lung disease." in: Arthritis and rheumatism, Vol. 63, Issue 8, pp. 2484-94, (2011) (PubMed).

Seltsam, Strigens, Levene, Yahalom, Moulds, Moulds, Hustinx, Weisbach, Figueroa, Bade-Doeding, DeLuca, Blasczyk: "The molecular diversity of Sema7A, the semaphorin that carries the JMH blood group antigens." in: Transfusion, Vol. 47, Issue 1, pp. 133-46, (2007) (PubMed).

Synonyms and alternative names related to SEMA7A

sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (Sema7a), semaphorin 7A (John Milton Hagen blood group) (Sema7a), semaphorin 7A (John Milton Hagen blood group) (SEMA7A), 2900057C09Rik, CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, M-Sema-L, SEMAK1, Semal, SEMAL

Protein level used designations for SEMA7A

  • H-Sema K1
  • Semaphorin K1
  • sema K1
  • sema L
  • semaphorin-7A
  • semaphorin-K1
  • semaphorin-L
  • sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
  • JMH blood group antigen
  • John Milton Hagen blood group H-Sema K1
  • john-Milton-Hargen human blood group Ag
  • sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)
  • sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A
  • semaphorin K1
  • semaphorin L
  • semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) isoform 1
  • semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) isoform 2
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