Asialoglycoprotein Receptor 2 antibody (AA 80-311)

Catalog No. ABIN7193549

The Mouse Monoclonal anti-Asialoglycoprotein Receptor 2 antibody has been validated for ELISA, IHC and FACS. It is suitable to detect Asialoglycoprotein Receptor 2 in samples from Human.

Quick Overview for Asialoglycoprotein Receptor 2 antibody (AA 80-311) (ABIN7193549)

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Asialoglycoprotein Receptor 2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2C6D11

Product Details anti-Asialoglycoprotein Receptor 2 Antibody

Binding Specificity: AA 80-311

Purpose: ASGR2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Alternative Name: ASGR2

Background:

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 35 kDa

Gene ID: 433

UniProt: P07307

Pathways: Thyroid Hormone Synthesis