CCR6 antibody

Catalog No. ABIN7193565

Product Details anti-CCR6 Antibody

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Purpose: CD196 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD196 expressed in E. Coli.

Clone: 7C6D9

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Alternative Name: CD196 (CCR6 Products)

Background:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

Molecular Weight: 42.5 kDa

Gene ID: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process