PAX8 antibody (AA 300-450)

Catalog No. ABIN7193596

This Mouse Monoclonal antibody specifically detects PAX8 in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for PAX8 antibody (AA 300-450) (ABIN7193596)

Target: PAX8 (Paired Box 8 (PAX8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX8 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 3E6B3

Product Details anti-PAX8 Antibody

Binding Specificity: AA 300-450

Purpose: PAX8 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PAX8 (AA: 300-450) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PAX8

Target: PAX8 (Paired Box 8 (PAX8))

Alternative Name: PAX8

Background:

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

Molecular Weight: 60 kDa

Gene ID: 7849

UniProt: P27930

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation