NEFH antibody (AA 2-251)
Quick Overview for NEFH antibody (AA 2-251) (ABIN7193620)
Target
See all NEFH AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 2-251
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Purpose
- NEFH Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human NEFH (AA: 2-251) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200-1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
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Alternative Name
- NEFH
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Background
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
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Molecular Weight
- 112.4 kDa
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Gene ID
- 4744
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UniProt
- P12036
Target
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