Gelsolin antibody
Quick Overview for Gelsolin antibody (ABIN7193641)
Target
See all Gelsolin (GSN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- GSN Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human GSN (AA: (673-783)) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200-1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Gelsolin (GSN)
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Alternative Name
- GSN
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Background
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The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
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Molecular Weight
- 85.7 kDa
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Gene ID
- 2934
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UniProt
- P06396
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
Target
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