Chromogranin A antibody (AA 278-457)

Catalog No. ABIN7193659

This Mouse Monoclonal antibody specifically detects Chromogranin A in IHC, FACS, WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Chromogranin A antibody (AA 278-457) (ABIN7193659)

Target: Chromogranin A (CHGA)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Chromogranin A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), ELISA

Clone: 5H10B12

Product Details anti-Chromogranin A Antibody

Binding Specificity: AA 278-457

Purpose: CHGA Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CHGA (AA: 278-457) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Chromogranin A

Target: Chromogranin A (CHGA)

Alternative Name: CHGA

Background:

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 50 kDa

Gene ID: 1113

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling