GLUL antibody (AA 2-121)

Catalog No. ABIN7193662

This Mouse Monoclonal antibody specifically detects GLUL in WB, ELISA, IHC, FACS and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for GLUL antibody (AA 2-121) (ABIN7193662)

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLUL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 2D11A2

Product Details anti-GLUL Antibody

Binding Specificity: AA 2-121

Purpose: GLUL Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GLUL (AA: 2-121) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for GLUL

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Alternative Name: GLUL

Background:

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Molecular Weight: 42 kDa

Gene ID: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion