PAX8 antibody (AA 60-261)

Catalog No. ABIN7193697

This anti-PAX8 antibody is a Mouse Monoclonal antibody detecting PAX8 in WB, IHC, ELISA and FACS. Suitable for Human.

Quick Overview for PAX8 antibody (AA 60-261) (ABIN7193697)

Target: PAX8 (Paired Box 8 (PAX8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 1A1D3

Product Details anti-PAX8 Antibody

Binding Specificity: AA 60-261

Purpose: PAX8 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PAX8 (AA: 60-261) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PAX8

Target: PAX8 (Paired Box 8 (PAX8))

Alternative Name: PAX8

Background:

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 48.2 kDa

Gene ID: 7849

UniProt: P27930

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation