F11R antibody (AA 28-238)
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- Target See all F11R Antibodies
- F11R (F11 Receptor (F11R))
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Binding Specificity
- AA 28-238
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This F11R antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD321 (AA: extra 28-238) expressed in E. coli.
- Clone
- 3B2B3
- Isotype
- IgG1
- Top Product
- Discover our top product F11R Primary Antibody
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- Application Notes
- WB:1:500 - 1:2000, IHC:1:200 - 1:1000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- F11R (F11 Receptor (F11R))
- Alternative Name
- CD321 (F11R Products)
- Synonyms
- CD321 antibody, JAM antibody, JAM1 antibody, JAMA antibody, JCAM antibody, KAT antibody, PAM-1 antibody, 9130004G24 antibody, AA638916 antibody, ESTM33 antibody, JAM-1 antibody, JAM-A antibody, Jcam antibody, Jcam1 antibody, Ly106 antibody, Jam1 antibody, F11 receptor antibody, F11R antibody, F11r antibody
- Background
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Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Aliases: F11R,JAM, KAT, JAM1, JAMA, JCAM, PAM-1
- Molecular Weight
- 32.6 kDa
- Gene ID
- 50848
- Pathways
- Cell-Cell Junction Organization
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