F11R antibody (AA 28-238)

Catalog No. ABIN7193767

This Mouse Monoclonal antibody specifically detects F11R in ELISA, IHC, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for F11R antibody (AA 28-238) (ABIN7193767)

Target: F11R (F11 Receptor (F11R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3B2B3

Product Details anti-F11R Antibody

Binding Specificity: AA 28-238

Purpose: CD321 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD321 (AA: 28-238) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: CD321

Background:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Molecular Weight: 32.6 kDa

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization