PDLIM7 antibody (AA 86-280)

Catalog No. ABIN7193840

The Mouse Monoclonal anti-PDLIM7 antibody has been validated for ELISA, IHC, ICC and FACS. It is suitable to detect PDLIM7 in samples from Human.

Quick Overview for PDLIM7 antibody (AA 86-280) (ABIN7193840)

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDLIM7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3B3B3

Product Details anti-PDLIM7 Antibody

Binding Specificity: AA 86-280

Purpose: PDLIM7 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PDLIM7 (AA: 86-280) expressed in HEK293-6e cells supernatant.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PDLIM7

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Alternative Name: PDLIM7

Background:

The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 49.8 kDa

UniProt: Q9NR12