Rab3a+Rab3b+Rab3c+Rab3d (AA 101-150) antibody (Biotin)

Catalog No. ABIN715378

This Rabbit Polyclonal antibody specifically detects Rab3a+Rab3b+Rab3c+Rab3d in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Rab3a+Rab3b+Rab3c+Rab3d (AA 101-150) antibody (Biotin) (ABIN715378)

Target: Rab3a+Rab3b+Rab3c+Rab3d

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 101-150

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rab3A+Rab3B+Rab3C+Rab3D

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Rab3a+Rab3b+Rab3c+Rab3d

Background:

Synonyms: RAB3A, RAB3A member RAS oncogene family, RAB3B, RAB3B member RAS oncogene family, RAB3C, RAB3C member RAS oncogene family, RAB3D member RAS oncogene family, RAD3D, Ras related protein Rab 3A, Ras related protein Rab 3B, Ras related protein Rab 3C, Ras related protein Rab 3D, D2 2, Glioblastoma overexpressed, GOV, RAB16.

Background: Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.