Renin antibody (AA 331-406) (HRP)

Catalog No. ABIN715445

The Rabbit Polyclonal anti-Renin antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect Renin in samples from Rat, Mouse and Dog.

Quick Overview for Renin antibody (AA 331-406) (HRP) (ABIN715445)

Target: Renin (REN)

Reactivity: Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Renin antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Renin Antibody (HRP)

Binding Specificity: AA 331-406

Cross-Reactivity: Dog, Mouse, Rat

Predicted Reactivity: Human,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Renin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Renin

Target: Renin (REN)

Alternative Name: Renin

Background:

Synonyms: HNFJ2, Renin, Angiotensinogenase, REN

Background: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

Gene ID: 5972

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour