RSPO1 antibody

Catalog No. ABIN715451

The Rabbit Polyclonal anti-RSPO1 antibody is suitable to detect RSPO1 in samples from Human, Rat and Mouse. It has been validated for WB, IHC (p) and IF (p).

Quick Overview for RSPO1 antibody (ABIN715451)

Target: RSPO1 (R-Spondin 1 (RSPO1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RSPO1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPO1

Isotype: IgG

Application Details

Application Notes: WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RSPO1

Target: RSPO1 (R-Spondin 1 (RSPO1))

Alternative Name: Rspo1

Background:

Synonyms: CRISTIN3, FLJ40906, hRspo1, R spondin homolog Xenopus laevis, R spondin homolog, R spondin1, R-spondin-1, Roof plate specic spondin, Roof plate-specic spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN.

Background: RSPO1 is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

Gene ID: 284654