SLITRK1 antibody (PE)

Catalog No. ABIN715566

This anti-SLITRK1 antibody is a Rabbit Polyclonal antibody detecting SLITRK1 in IF (p). Suitable for Rat, Human, Mouse, Cow, Dog, Pig and Chicken.

Quick Overview for SLITRK1 antibody (PE) (ABIN715566)

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Reactivity: Rat, Human, Mouse, Cow, Dog, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK1 antibody is conjugated to PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SLITRK1 Antibody (PE)

Specificity: Excitation / Emission Wavelengths: 565nm/578nm

Cross-Reactivity: Rat (Rattus), Chicken, Dog (Canine), Pig (Porcine), Cow (Bovine)

Purification: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human Slitrk1

Isotype: IgG

Application Details

Comment:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4 °C for 12 months

Expiry Date: 12 months

Target Details for SLITRK1

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Alternative Name: Slitrk1

Background: Slitrk1 is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Touretteﾒs Syndrome, it is thought to play only a minor role if at all.

Molecular Weight: 78-88kDa

Gene ID: 114798