Quick Overview for CD45RO antibody (PerCP-Cy5.5) (ABIN7200552)
Target
CD45RO
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
This CD45RO antibody is conjugated to PerCP-Cy5.5
Application
Flow Cytometry (FACS)
Grade
GMP Grade
Clone
UCHL1
Purpose
CD45RO PerCP-Cyanine5.5 Antibody
Characteristics
The clone UCHL1 recognizes 180-185 KD surface antigen known as CD45RO commonly expressed by thymocytes, a subset of resting, memory and activated T cells, activated monocytes/macrophages, granulocytes and myeloma cells. CD45RO is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. It plays important rule in development of lymphocytes and antigen signaling, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.