Recombinant TNF alpha (Infliximab Biosimilar) antibody

Catalog No. ABIN7200661

The Mouse Monoclonal anti-TNF alpha (Infliximab Biosimilar) antibody (Clone cA2) (ABIN7200661) specifically detects TNF alpha (Infliximab Biosimilar) in FACS and in vivo. The antibody is reactive with Human samples.

Quick Overview for Recombinant TNF alpha (Infliximab Biosimilar) antibody (ABIN7200661)

Target: TNF alpha (Infliximab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha (Infliximab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade: Research Grade

Clone: CA2

Product Details anti-TNF alpha (Infliximab Biosimilar) Antibody

Purpose: Infliximab Biosimilar, TNF alpha Monoclonal Antibody

Specificity: The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.

Characteristics: Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell. Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction. Syd Labs also provides the following anti-TNF antibody biosimilar protein:

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Sterility: 0.2 μm filtered

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.

Isotype: IgG1

Application Details

Application Notes: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Buffer: PBS, pH 7.4, no stabilizers or preservatives.

Preservative: Without preservative

Storage: 4°C,-20 °C

Storage Comment: 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

Expiry Date: 12 months

Target Details for TNF alpha (Infliximab Biosimilar)

Target: TNF alpha (Infliximab Biosimilar)

Alternative Name: Infliximab Biosimilar

Target Type: Biosimilar