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Recombinant TNF alpha (Infliximab Biosimilar) antibody

This anti-TNF alpha (Infliximab Biosimilar) antibody is a Mouse Monoclonal antibody detecting TNF alpha (Infliximab Biosimilar) in FACS and in vivo. Suitable for Human.
Catalog No. ABIN7200661

Quick Overview for Recombinant TNF alpha (Infliximab Biosimilar) antibody (ABIN7200661)

Target

TNF alpha (Infliximab Biosimilar)

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

  • 1
  • 1
  • 1
  • 1
Mouse

Clonality

  • 3
  • 1
Monoclonal

Conjugate

  • 4
This TNF alpha (Infliximab Biosimilar) antibody is un-conjugated

Application

  • 4
  • 3
  • 3
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade

Research Grade

Clone

CA2
  • Purpose

    Infliximab Biosimilar, TNF alpha Monoclonal Antibody

    Specificity

    The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.

    Characteristics

    Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell. Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction. Syd Labs also provides the following anti-TNF antibody biosimilar protein:

    Purification

    Protein A or G affinity column

    Purity

    >95 % by reducing SDS-PAGE

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogen

    The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.

    Isotype

    IgG1
  • Application Notes

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Preservative

    Without preservative

    Storage

    4°C,-20 °C

    Storage Comment

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Expiry Date

    12 months
  • Target

    TNF alpha (Infliximab Biosimilar)

    Alternative Name

    Infliximab Biosimilar

    Target Type

    Biosimilar
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