Recombinant TNF alpha (Infliximab Biosimilar) antibody

Catalog No. ABIN7200661

This anti-TNF alpha (Infliximab Biosimilar) antibody is a Mouse Monoclonal antibody detecting TNF alpha (Infliximab Biosimilar) in FACS and in vivo. Suitable for Human.

Quick Overview for Recombinant TNF alpha (Infliximab Biosimilar) antibody (ABIN7200661)

Target: TNF alpha (Infliximab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha (Infliximab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Clone: CA2

Product Details anti-TNF alpha (Infliximab Biosimilar) Antibody

Purpose: Infliximab Biosimilar, TNF alpha Monoclonal Antibody

Specificity: The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.

Characteristics: Recombinant Chimeric IgG1 Monoclonal Antibody.

Purification: Protein A affinity column

Purity: > 95% by SDS-PAGE under reducing conditions and HPLC.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method.

Immunogen: The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.

Isotype: IgG1 kappa

Application Details

Application Notes: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, no stabilizers or preservatives.

Preservative: Without preservative

Handling Advice: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

Expiry Date: 12 months

Target Details for TNF alpha (Infliximab Biosimilar)

Target: TNF alpha (Infliximab Biosimilar)

Target Type: Biosimilar

Background: Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell.

Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction.