This anti-TNF alpha (Infliximab Biosimilar) antibody is a Mouse Monoclonal antibody detecting TNF alpha (Infliximab Biosimilar) in FACS and in vivo. Suitable for Human.
Catalog No. ABIN7200661
Quick Overview for Recombinant TNF alpha (Infliximab Biosimilar) antibody (ABIN7200661)
Target
TNF alpha (Infliximab Biosimilar)
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
This TNF alpha (Infliximab Biosimilar) antibody is un-conjugated
The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.
Characteristics
Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell. Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction. Syd Labs also provides the following anti-TNF antibody biosimilar protein:
Purification
Protein A or G affinity column
Purity
>95 % by reducing SDS-PAGE
Sterility
0.2 μm filtered
Endotoxin Level
< 1 EU per 1 mg of the protein by the LAL method
Immunogen
The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.
Research Grade
Reactivity: Human
ELISA, WB
Host: Mammalian Cells
Monoclonal
unconjugated
Recombinant Antibody
Application Notes
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.
Restrictions
For Research Use only
Format
Liquid
Concentration
> 3 mg/mL
Buffer
PBS, pH 7.4, no stabilizers or preservatives.
Preservative
Without preservative
Storage
4°C,-20 °C
Storage Comment
12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.