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Recombinant EGFR (Panitumumab Biosimilar) antibody

This Mouse Monoclonal antibody specifically detects EGFR (Panitumumab Biosimilar) in FACS and in vivo. It exhibits reactivity toward Human.
Catalog No. ABIN7200662

Quick Overview for Recombinant EGFR (Panitumumab Biosimilar) antibody (ABIN7200662)

Target

EGFR (Panitumumab Biosimilar)

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

  • 1
  • 1
Mouse

Clonality

  • 2
Monoclonal

Conjugate

  • 2
This EGFR (Panitumumab Biosimilar) antibody is un-conjugated

Application

Flow Cytometry (FACS), In vivo Studies (in vivo)
  • Purpose

    Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody

    Specificity

    The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.

    Characteristics

    Recombinant Humanized IgG2 Monoclonal Antibody.

    Purification

    Protein A affinity column

    Purity

    > 95% by SDS-PAGE under reducing conditions and HPLC.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 1 EU per 1 mg of the protein by the LAL method.

    Immunogen

    The monoclonal antibody panitumumab biosimilar was produced in the Panitumumab biosimilar CHO stable cell line.

    Isotype

    IgG2 kappa
  • Application Notes

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Preservative

    Without preservative

    Handling Advice

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Expiry Date

    12 months
  • Target

    EGFR (Panitumumab Biosimilar)

    Target Type

    Biosimilar

    Background

    Panitumumab, a fully anti-EGFR (epidermal growth factor receptor, EGF receptor, ErbB-1 and HER1 in humans) human monoclonal antibody, is used for the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS".
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