YWHAB/YWHAZ antibody
Quick Overview for YWHAB/YWHAZ antibody (ABIN7224964)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- 14-3-3 β/ζ Polyclonal Antibody
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Specificity
- 14-3-3 β/ζ Polyclonal Antibody detects endogenous levels of 14-3-3 β/ζ protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human 14-3-3 beta/zeta around the non-phosphorylation site of S184/186
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))
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Alternative Name
- 14-3-3 beta/zeta
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Background
- Rabbit Anti-14-3-3 β/ζ Polyclonal Antibody,YWHAZ, 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAB, 14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1,YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for YWHAZ.,14-3-3 protein beta
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Gene ID
- 7534, 7529
Target
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