ADA antibody (AA 80-160)

Catalog No. ABIN7227210

This Rabbit Polyclonal antibody specifically detects ADA in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADA antibody (AA 80-160) (ABIN7227210)

Target: ADA (Adenosine Deaminase (ADA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADA Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-ADA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ADA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ADA protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADA

Target: ADA (Adenosine Deaminase (ADA))

Alternative Name: ADA

Background: Adenosine deaminase, Adenosine aminohydrolaseADA (Adenosine Deaminase) is a Protein Coding gene. Diseases associated with ADA include Severe Combined Immunodeficiency Due To Ada Deficiency and Adenosine Deaminase Deficiency. Among its related pathways are Metabolism and One carbon pool by folate. ADA encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for ADA and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Molecular Weight: 39kD

Gene ID: 100

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process