ARFGAP3 antibody (AA 280-360)
Quick Overview for ARFGAP3 antibody (AA 280-360) (ABIN7221002)
Target
See all ARFGAP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 280-360
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Purpose
- ARF GAP3 Polyclonal Antibody
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Specificity
- ARF GAP3 Polyclonal Antibody detects endogenous levels of ARF GAP3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human ARF GAP3 at AA range: 280-360
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Alternative Name
- ARF GAP3
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Background
- Rabbit Anti-ARF GAP3 Polyclonal Antibody,ARFGAP3, ARFGAP1, ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3,The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. ARFGAP3 was originally known as ARFGAP1, but that is now the name of a related but different gene.,ADP-ribosylation factor GTPase-activating protein 3
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Gene ID
- 26286
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UniProt
- Q9NP61
Target
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