Adrenomedullin antibody (Internal Region)

Catalog No. ABIN7219580

This anti-Adrenomedullin antibody is a Rabbit Polyclonal antibody detecting Adrenomedullin in ELISA and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for Adrenomedullin antibody (Internal Region) (ABIN7219580)

Target: Adrenomedullin (ADM)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adrenomedullin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Adrenomedullin Antibody

Binding Specificity: Internal Region

Purpose: ADM Polyclonal Antibody

Specificity: ADM Polyclonal Antibody detects endogenous levels of ADM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ADM

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Adrenomedullin

Target: Adrenomedullin (ADM)

Alternative Name: ADM

Target Type: Hormone

Background: Rabbit Anti-ADM Polyclonal Antibody,ADM, AM, ADM,The adrenomedullin encoded by ADM is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E.coli and S. aureus at low concentration.,ADM

Gene ID: 133

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation