Adrenomedullin antibody (AA 50-150)

Catalog No. ABIN7265507

The Rabbit Polyclonal anti-Adrenomedullin antibody is suitable to detect Adrenomedullin in samples from Human. It has been validated for WB.

Quick Overview for Adrenomedullin antibody (AA 50-150) (ABIN7265507)

Target: Adrenomedullin (ADM)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adrenomedullin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adrenomedullin Antibody

Binding Specificity: AA 50-150

Purpose: ADM Rabbit pAb

Sequence: SSYPTGLADV KAGPAQTLIR PQDMKGASRS PEDSSPDAAR IRVKRYRQSM NNFQGLRSFG CRFGTCTVQK LAHQIYQFTD KDKDNVAPRS KISPQGYGRR R

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ADM (NP_001115.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Adrenomedullin

Target: Adrenomedullin (ADM)

Alternative Name: ADM

Target Type: Hormone

Background: The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration.,ADM,AM,PAMP,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,Cardiovascular,Angiogenesis,Hypoxia,ADM

Molecular Weight: 20kDa

Gene ID: 133

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation