AK1C4 antibody (AA 1-80)

Catalog No. ABIN7227252

This Rabbit Polyclonal antibody specifically detects AK1C4 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for AK1C4 antibody (AA 1-80) (ABIN7227252)

Target: AK1C4 (LOC105224584) (Aldo-Keto Reductase Family 1 Member C1 Homolog (LOC105224584))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AK1C4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-AK1C4 Antibody

Binding Specificity: AA 1-80

Purpose: AK1C4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AK1C4 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human AK1C4 protein at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for AK1C4

Target: AK1C4 (LOC105224584) (Aldo-Keto Reductase Family 1 Member C1 Homolog (LOC105224584))

Alternative Name: AK1C4

Background: Rabbit Anti-AK1C4 Polyclonal Antibody,Aldo-keto reductase family 1 member C4, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, CDR, Dihydrodiol dehydrogenase 4, DD-4, DD4,AKR1C4 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.,AK1C4

Gene ID: 1109

UniProt: P17516