ANAPC5 antibody (AA 120-200)

Catalog No. ABIN7213622

The Rabbit Polyclonal anti-ANAPC5 antibody has been validated for WB and ELISA. It is suitable to detect ANAPC5 in samples from Human.

Quick Overview for ANAPC5 antibody (AA 120-200) (ABIN7213622)

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANAPC5 Antibody

Binding Specificity: AA 120-200

Purpose: APC5 Polyclonal Antibody

Specificity: APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human APC5 at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ANAPC5

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Alternative Name: APC5

Background: Rabbit Anti-APC5 Polyclonal Antibody,ANAPC5, APC5, Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5,ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.,Anaphase-promoting complex subunit 5

Gene ID: 51433

UniProt: Q9UJX4

Pathways: M Phase