Annexin VII antibody (Internal Region)

Catalog No. ABIN7218278

The Rabbit Polyclonal anti-Annexin VII antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect Annexin VII in samples from Human and Mouse.

Quick Overview for Annexin VII antibody (Internal Region) (ABIN7218278)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VII antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Annexin VII Antibody

Binding Specificity: Internal Region

Purpose: Annexin VII Polyclonal Antibody

Specificity: Annexin VII Polyclonal Antibody detects endogenous levels of Annexin VII protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Annexin VII

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: Annexin VII

Background: Rabbit Anti-Annexin VII Polyclonal Antibody,ANXA7, ANX7, SNX, OK/SW-cl.95, Annexin A7, Annexin VII, Annexin-7, Synexin,Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2. and 2. kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.,Annexin A7

Gene ID: 310

UniProt: P20073