AP2 alpha/beta (AA 360-440) antibody

Catalog No. ABIN7213610

The Rabbit Polyclonal anti-AP2 alpha/beta antibody is suitable to detect AP2 alpha/beta in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC (p).

Quick Overview for AP2 alpha/beta (AA 360-440) antibody (ABIN7213610)

Target: AP2 alpha/beta

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 360-440

Purpose: AP-2α/β Polyclonal Antibody

Specificity: AP-2α/β Polyclonal Antibody detects endogenous levels of AP-2α/β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human AP-2alpha/beta at AA range: 360-440

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: AP2 alpha/beta

Alternative Name: AP-2alpha/beta

Background: Rabbit Anti-AP-2α/β Polyclonal Antibody,TFAP2A, AP2TF, TFAP2, Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, TFAP2B, Transcription factor AP-2-beta, AP2-beta, Activating enhancer-bindi,Transcription factor AP-2 alpha encoded by TFAP2A is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for TFAP2A.,Transcription factor AP-2-alpha

Gene ID: 7020