APITD1 antibody (AA 70-150)

Catalog No. ABIN7227850

This Rabbit Polyclonal antibody specifically detects APITD1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for APITD1 antibody (AA 70-150) (ABIN7227850)

Target: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APITD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APITD1 Antibody

Binding Specificity: AA 70-150

Purpose: CENPS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CENPS protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CENPS protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for APITD1

Target: APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

Alternative Name: CENPS

Background: Rabbit Anti-CENPS Polyclonal Antibody,Centromere protein S, CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-associated histone fold protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa,CENPS (Centromere Protein S) was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. CENPS was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants.,CENPS

Molecular Weight: observerd band 15kDa

Gene ID: 100526739

UniProt: Q8N2Z9