Atrophin 1 antibody (AA 50-130)

Catalog No. ABIN7213736

This Rabbit Polyclonal antibody specifically detects Atrophin 1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Atrophin 1 antibody (AA 50-130) (ABIN7213736)

Target: Atrophin 1 (ATN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Atrophin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Atrophin 1 Antibody

Binding Specificity: AA 50-130

Purpose: Atrophin-1 Polyclonal Antibody

Specificity: Atrophin-1 Polyclonal Antibody detects endogenous levels of Atrophin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Atrophin-1 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Atrophin 1

Target: Atrophin 1 (ATN1)

Alternative Name: Atrophin-1

Background: Rabbit Anti-Atrophin-1 Polyclonal Antibody,ATN1, D12S755E, DRPLA, Atrophin-1, Dentatorubral-pallidoluysian atrophy protein,Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.,Atrophin-1

Gene ID: 1822

UniProt: P54259