Atrophin 1 antibody (N-Term)

Catalog No. ABIN6256956

Product Details anti-Atrophin 1 Antibody

Target: Atrophin 1 (ATN1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Atrophin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: Atrophin 1 Antibody detects endogenous levels of total Atrophin 1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Atrophin 1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Atrophin 1

Target: Atrophin 1 (ATN1)

Alternative Name: ATN1 (ATN1 Products)

Synonyms: B37 antibody, D12S755E antibody, DRPLA antibody, HRS antibody, NOD antibody, Atr1 antibody, Drpla antibody, atrophin-1 antibody, RERE antibody, ATN1 antibody, atrophin 1 antibody, ATN1 antibody, Atn1 antibody

Background:

Description: Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Gln (polyQ) repeats.

Gene: ATN1

Molecular Weight: 130 kDa

Gene ID: 1822

UniProt: P54259