Autoimmune Myocardial Disease antibody (AA 380-460)
Quick Overview for Autoimmune Myocardial Disease antibody (AA 380-460) (ABIN7227276)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 380-460
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Purpose
- AMD Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of AMD protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human AMD protein at AA range: 380-460
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Autoimmune Myocardial Disease (AMD)
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Alternative Name
- AMD
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Background
- Rabbit Anti-AMD Polyclonal Antibody,Peptidylamidoglycolate lyase, PAL,PAM encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,AMD
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Gene ID
- 5066
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UniProt
- P19021
Target
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