BCOR antibody (AA 1200-1280)
Quick Overview for BCOR antibody (AA 1200-1280) (ABIN7213792)
Target
See all BCOR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1200-1280
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Purpose
- BCoR Polyclonal Antibody
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Specificity
- BCoR Polyclonal Antibody detects endogenous levels of BCoR protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human BCoR at AA range: 1200-1280
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BCOR (BCL6 Co-Repressor (BCOR))
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Alternative Name
- BCoR
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Background
- Rabbit Anti-BCoR Polyclonal Antibody,BCOR, KIAA1575, BCL-6 corepressor, BCoR,The protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for BCOR. A pseudogene of this gene is found on chromosome Y.,BCL-6 corepressor
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Gene ID
- 54880
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UniProt
- Q6W2J9
Target
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