BCOR antibody (AA 1107-1137)

Catalog No. ABIN391538

The Rabbit Polyclonal anti-BCOR antibody is suitable to detect BCOR in samples from Human and Mouse. It has been validated for WB, IHC (p) and FACS.

Quick Overview for BCOR antibody (AA 1107-1137) (ABIN391538)

Target: BCOR (BCL6 Co-Repressor (BCOR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCOR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB19040

Product Details anti-BCOR Antibody

Binding Specificity: AA 1107-1137

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1137 amino acids from the Central region of human BCOR.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:500. IHC-P: 1:50~100. IHC: 1:50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for BCOR

Target: BCOR (BCL6 Co-Repressor (BCOR))

Alternative Name: BCOR

Background: BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.

Molecular Weight: 192189

Gene ID: 54880

NCBI Accession: NP_001116855, NP_001116856, NP_001116857, NP_060215

UniProt: Q6W2J9