BEND4 antibody (AA 340-420)
Quick Overview for BEND4 antibody (AA 340-420) (ABIN7214024)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 340-420
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Purpose
- CCDC4 Polyclonal Antibody
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Specificity
- CCDC4 Polyclonal Antibody detects endogenous levels of CCDC4 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human CCDC4 at AA range: 340-420
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BEND4 (BEN Domain Containing 4 (BEND4))
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Alternative Name
- CCDC4
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Background
- Rabbit Anti-CCDC4 Polyclonal Antibody,BEND4, CCDC4, BEN domain-containing protein 4, Coiled-coil domain-containing protein 4,BEND4 (BEN domain-containing protein 4) is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein-DNA and protein-protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.,BEN domain-containing protein 4
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Molecular Weight
- observerd band 57kDa
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Gene ID
- 389206
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UniProt
- Q6ZU67
Target
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