BMP8A antibody (AA 230-310)

Catalog No. ABIN7213826

The Rabbit Polyclonal anti-BMP8A antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect BMP8A in samples from Human.

Quick Overview for BMP8A antibody (AA 230-310) (ABIN7213826)

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BMP8A Antibody

Binding Specificity: AA 230-310

Purpose: BMP-8A Polyclonal Antibody

Specificity: BMP-8A Polyclonal Antibody detects endogenous levels of BMP-8A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human BMP-8A at AA range: 230-310

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BMP8A

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Alternative Name: BMP-8A

Background: Rabbit Anti-BMP-8A Polyclonal Antibody,BMP8A, Bone morphogenetic protein 8A, BMP-8A,BMP8A encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. BMP8A may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.,Bone morphogenetic protein 8A

Molecular Weight: observerd band 45kDa

Gene ID: 353500

UniProt: Q7Z5Y6

Pathways: Negative Regulation of Hormone Secretion