BCAS3 antibody (AA 660-740)

Catalog No. ABIN7223322

This Rabbit Polyclonal antibody specifically detects BCAS3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for BCAS3 antibody (AA 660-740) (ABIN7223322)

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCAS3 Antibody

Binding Specificity: AA 660-740

Purpose: BCAS3 Polyclonal Antibody

Specificity: BCAS3 Polyclonal Antibody detects endogenous levels of BCAS3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BCAS3 at AA range: 660-740

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BCAS3

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Alternative Name: BCAS3

Background: Rabbit Anti-BCAS3 Polyclonal Antibody,BCAS3, Breast carcinoma-amplified sequence 3, GAOB1,Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98 % identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23. BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers. It is reported to be a target of metastasis associated protein-1 (MTA-1). Further BCAS3 expression is also upregulated in grade III and IV glioblastomas where it is misexpressed in the tumor cells.,Breast carcinoma-amplified sequence 3

Gene ID: 54828

UniProt: Q9H6U6