BTBD6 antibody (AA 60-140)

Catalog No. ABIN7225764

The Rabbit Polyclonal anti-BTBD6 antibody is suitable to detect BTBD6 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC (p).

Quick Overview for BTBD6 antibody (AA 60-140) (ABIN7225764)

Target: BTBD6 (BTB (POZ) Domain Containing 6 (BTBD6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BTBD6 Antibody

Binding Specificity: AA 60-140

Purpose: BTBD6 Polyclonal Antibody

Specificity: BTBD6 Polyclonal Antibody detects endogenous levels of BTBD6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BTBD6 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BTBD6

Target: BTBD6 (BTB (POZ) Domain Containing 6 (BTBD6))

Alternative Name: BTBD6

Background: Rabbit Anti-BTBD6 Polyclonal Antibody,BTBD6, BDPL, BTB/POZ domain-containing protein 6, Lens BTB domain protein,BTBD6 (BTB/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB/POZ domain and is specifically expressed in the lens. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens.,BTB

Molecular Weight: observerd band 45kDa

Gene ID: 90135

UniProt: Q96KE9