BTN3A1/2/3 antibody (AA 41-90)

Catalog No. ABIN7227532

This anti-BTN3A1/2/3 antibody is a Rabbit Polyclonal antibody detecting BTN3A1/2/3 in ELISA and IHC (p). Suitable for Human.

Quick Overview for BTN3A1/2/3 antibody (AA 41-90) (ABIN7227532)

Target: BTN3A1/2/3

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTN3A1/2/3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BTN3A1/2/3 Antibody

Binding Specificity: AA 41-90

Purpose: BTN3A1/2/3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of BTN3A1/2/3

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human BTN3A1/2/3 protein at AA range: 41-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BTN3A1/2/3

Target: BTN3A1/2/3

Background: Rabbit Anti-BTN3A1/2/3 Polyclonal Antibody,Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5,The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g. BTN2A1, MIM 613590) and BTN3 (e.g. BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al. 2010 [PubMed 20208008]). BTN3A1 (Butyrophilin Subfamily 3 Member A1) is a Protein Coding gene. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Butyrophilin (BTN) family interactions. An important paralog of BTN3A1 is BTN3A3.,BTN3A1/2/3

Gene ID: 11119