N-Cadherin antibody (AA 690-770)

Catalog No. ABIN7215970

The Rabbit Polyclonal anti-N-Cadherin antibody has been validated for WB, IF, ELISA and IHC (p). It is suitable to detect N-Cadherin in samples from Human, Mouse and Rat.

Quick Overview for N-Cadherin antibody (AA 690-770) (ABIN7215970)

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This N-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-N-Cadherin Antibody

Binding Specificity: AA 690-770

Purpose: N-cadherin Polyclonal Antibody

Specificity: N-cadherin Polyclonal Antibody detects endogenous levels of N-cadherin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human N-cadherin at AA range: 690-770

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for N-Cadherin

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Alternative Name: N-cadherin

Background: Rabbit Anti-N-cadherin Polyclonal Antibody,CDH2, CDHN, NCAD, Cadherin-2, CDw325, Neural cadherin, N-cadherin, CD antigen CD325,CDH2 encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. Cadherin-2 plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.,Cadherin-2

Molecular Weight: observerd band 140kDa

Gene ID: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane