Cadherin 7 antibody (AA 620-700)

Catalog No. ABIN7213912

The Rabbit Polyclonal anti-Cadherin 7 antibody is suitable to detect Cadherin 7 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for Cadherin 7 antibody (AA 620-700) (ABIN7213912)

Target: Cadherin 7 (CDH7)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cadherin 7 Antibody

Binding Specificity: AA 620-700

Purpose: Cadherin-7 Polyclonal Antibody

Specificity: Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Cadherin-7 at AA range: 620-700

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Cadherin 7

Target: Cadherin 7 (CDH7)

Alternative Name: Cadherin-7

Background: Rabbit Anti-Cadherin-7 Polyclonal Antibody,CDH7, CDH7L1, Cadherin-7,CDH7 encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in CDH7 may be associated with bipolar disease in human patients. CDH7 is present in a gene cluster on chromosome 18.,Cadherin-7

Molecular Weight: observerd band 87kDa

Gene ID: 1005

UniProt: Q9ULB5

Pathways: Cell-Cell Junction Organization