Cadherin 8 antibody (AA 460-540)

Catalog No. ABIN7218878

This anti-Cadherin 8 antibody is a Rabbit Polyclonal antibody detecting Cadherin 8 in WB, ELISA, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for Cadherin 8 antibody (AA 460-540) (ABIN7218878)

Target: Cadherin 8 (CDH8)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cadherin 8 Antibody

Binding Specificity: AA 460-540

Purpose: Cadherin-8 Polyclonal Antibody

Specificity: Cadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Cadherin-8 at AA range: 460-540

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Cadherin 8

Target: Cadherin 8 (CDH8)

Alternative Name: Cadherin-8

Background: Rabbit Anti-Cadherin-8 Polyclonal Antibody,CDH8, Cadherin-8,CDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.,Cadherin-8

Molecular Weight: observerd band 90kDa

Gene ID: 1006

UniProt: P55286

Pathways: Cell-Cell Junction Organization