Calpain 9 antibody (AA 450-530)

Catalog No. ABIN7219140

This anti-Calpain 9 antibody is a Rabbit Polyclonal antibody detecting Calpain 9 in WB and ELISA. Suitable for Human.

Quick Overview for Calpain 9 antibody (AA 450-530) (ABIN7219140)

Target: Calpain 9 (CAPN9)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Calpain 9 Antibody

Binding Specificity: AA 450-530

Purpose: Calpain 9 Polyclonal Antibody

Specificity: Calpain 9 Polyclonal Antibody detects endogenous levels of Calpain 9 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Calpain 9 at AA range: 450-530

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Calpain 9

Target: Calpain 9 (CAPN9)

Alternative Name: Calpain 9

Background: Rabbit Anti-Calpain 9 Polyclonal Antibody,CAPN9, NCL4, Calpain-9, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36,Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The calpain 9 encoded by CAPN9 is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for CAPN9.,Calpain-9

Molecular Weight: observerd band 75kDa

Gene ID: 10753

UniProt: O14815