CA4 antibody (Internal Region)
Quick Overview for CA4 antibody (Internal Region) (ABIN7217806)
Target
See all CA4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Purpose
- CA IV Polyclonal Antibody
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Specificity
- CA IV Polyclonal Antibody detects endogenous levels of CA IV protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human CA IV
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CA4 (Carbonic Anhydrase IV (CA4))
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Alternative Name
- CA IV
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Background
- Rabbit Anti-CA IV Polyclonal Antibody,CA4, Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV,Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA4 encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.,Carbonic anhydrase 4
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Molecular Weight
- observerd band 35kDa
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Gene ID
- 762
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UniProt
- P22748
Target
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