CA4 antibody (C-Term)

Catalog No. ABIN2776800

Product Details anti-CA4 Antibody

Target: CA4 (Carbonic Anhydrase IV (CA4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AFSQKLYYDK EQTVSMKDNV RPLQQLGQRT VIKSGAPGRP LPWALPALLG

Predicted Reactivity: Cow: 83%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 85%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CA4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 312 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CA4 antibody (ABIN2776800)

Sun, Yang, Feng, Sun, Zhu, Zhang, Jiang, Li, Gao, Zhang, Wang, Kong, Jin, Fu, Jin: "Temporal and parental-specific expression of imprinted genes in a newly derived Chinese human embryonic stem cell line and embryoid bodies." in: Human molecular genetics, Vol. 15, Issue 1, pp. 65-75, (2005) (PubMed).

Target Details for CA4

Target: CA4 (Carbonic Anhydrase IV (CA4))

Alternative Name: CA4 (CA4 Products)

Synonyms: CAIV antibody, Car4 antibody, RP17 antibody, AW456718 antibody, Ca4 antibody, ca4 antibody, caiv antibody, car4 antibody, rp17 antibody, CA4 antibody, zgc:171842 antibody, carbonic anhydrase 4 antibody, carbonic anhydrase 4 S homeolog antibody, carbonic anhydrase IV a antibody, CA4 antibody, Car4 antibody, ca4 antibody, ca4.S antibody, Ca4 antibody, ca4a antibody

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
Alias Symbols: CAIV, Car4, RP17
Protein Interaction Partner: PIH1D1, PRDX2, Htt, SLC4A4, SLC4A1, SLC4A3,
Protein Size: 312

Molecular Weight: 34 kDa

Gene ID: 762

NCBI Accession: NM_000717, NP_000708

UniProt: P22748