Cardiotrophin 1 antibody (AA 151-200)

Catalog No. ABIN7227598

The Rabbit Polyclonal anti-Cardiotrophin 1 antibody has been validated for WB and ELISA. It is suitable to detect Cardiotrophin 1 in samples from Human, Rat and Mouse.

Quick Overview for Cardiotrophin 1 antibody (AA 151-200) (ABIN7227598)

Target: Cardiotrophin 1 (CTF1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cardiotrophin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cardiotrophin 1 Antibody

Binding Specificity: AA 151-200

Purpose: Cardiotrophin-1 Polyclonal Antibody

Specificity: This antibody detects endogenous levels of Cardiotrophin-1

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Cardiotrophin-1 protein at AA range: 151-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Cardiotrophin 1

Target: Cardiotrophin 1 (CTF1)

Alternative Name: Cardiotrophin-1

Background: Rabbit Anti-Cardiotrophin-1 Polyclonal Antibody,Cardiotrophin-1, CT-1,CTF1 (Cardiotrophin 1) is a Protein Coding gene. Diseases associated with CTF1 include Neonatal Stroke and Hypertensive Heart Disease. Among its related pathways are Jak-STAT signaling pathway (KEGG) and NFAT and Cardiac Hypertrophy. The protein encoded by CTF1 is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for CTF1.,Cardiotrophin-1

Molecular Weight: observerd band 23kDa

Gene ID: 1489

UniProt: Q16619

Pathways: JAK-STAT Signaling