CLK4 antibody (AA 70-150)

Catalog No. ABIN7214248

This anti-CLK4 antibody is a Rabbit Polyclonal antibody detecting CLK4 in WB, ELISA and IHC (p). Suitable for Mouse and Human.

Quick Overview for CLK4 antibody (AA 70-150) (ABIN7214248)

Target: CLK4 (CDC-Like Kinase 4 (CLK4))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CLK4 Antibody

Binding Specificity: AA 70-150

Purpose: CLK4 Polyclonal Antibody

Specificity: CLK4 Polyclonal Antibody detects endogenous levels of CLK4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CLK4 at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CLK4

Target: CLK4 (CDC-Like Kinase 4 (CLK4))

Alternative Name: CLK4

Background: Rabbit Anti-CLK4 Polyclonal Antibody,CLK4, Dual specificity protein kinase CLK4, CDC-like kinase 4,CDC like kinase 4 encoded by CLK4 belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.,Dual specificity protein kinase CLK4

Molecular Weight: observerd band 65kDa

Gene ID: 57396

UniProt: Q9HAZ1