Cdc14A Phosphatase (Internal Region) antibody

Catalog No. ABIN7225542

This Rabbit Polyclonal antibody specifically detects Cdc14A Phosphatase in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Cdc14A Phosphatase (Internal Region) antibody (ABIN7225542)

Target: Cdc14A Phosphatase

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Cdc14a phosphatase Polyclonal Antibody

Specificity: Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cdc14a phosphatase

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Cdc14A Phosphatase

Background: CDC14A, Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog AThe protein encoded by CDC14A (cell division cycle 14A) is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms.

Molecular Weight: 66kD

Gene ID: 8556

UniProt: Q9UNH5