CDC23 antibody (AA 220-300)

Catalog No. ABIN7214098

This anti-CDC23 antibody is a Rabbit Polyclonal antibody detecting CDC23 in WB and ELISA. Suitable for Human, Mouse and Monkey.

Quick Overview for CDC23 antibody (AA 220-300) (ABIN7214098)

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDC23 Antibody

Binding Specificity: AA 220-300

Purpose: Cdc23 Polyclonal Antibody

Specificity: Cdc23 Polyclonal Antibody detects endogenous levels of Cdc23 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Cdc23 at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Alternative Name: Cdc23

Background: Rabbit Anti-Cdc23 Polyclonal Antibody,CDC23, ANAPC8, Cell division cycle protein 23 homolog, Anaphase-promoting complex subunit 8, APC8, Cyclosome subunit 8,Cell division cycle 23 encoded by CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.,Cell division cycle protein 23 homolog

Molecular Weight: observerd band 69kDa

Gene ID: 8697

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus