CENPI antibody (AA 10-90)

Catalog No. ABIN7227830

This anti-CENPI antibody is a Rabbit Polyclonal antibody detecting CENPI in WB and ELISA. Suitable for Human.

Quick Overview for CENPI antibody (AA 10-90) (ABIN7227830)

Target: CENPI (Centromere Protein I (CENPI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPI antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CENPI Antibody

Binding Specificity: AA 10-90

Purpose: CENPI Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CENPI protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CENPI protein at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CENPI

Target: CENPI (Centromere Protein I (CENPI))

Alternative Name: CENPI

Background: Rabbit Anti-CENPI Polyclonal Antibody,Centromere protein I, CENP-I, FSH primary response protein 1, Follicle-stimulating hormone primary response protein, Interphase centromere complex protein 19, Leucine-rich primary response protein 1,CENPI (Centromere Protein I) encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of CENPI is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of CENPI is found on chromosome 13.,CENPI

Molecular Weight: observerd band 83kDa

Gene ID: 2491

UniProt: Q92674